Peptide Database

Peptide NameHez-kinin-3

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC45H67N11O10

DescriptionStandard

        KVKFSAWG
    

Molecular Weight922.08 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.2198

GRAVY Index-0.14

Hydrophobic Moment 0.03

Boman Index0.12

Instability Index-18.43

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 355.08

LogP -1.68

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 29.0

Heavy Atoms 66.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018232 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa zea [Animal]

FamilyHez-kinin

Tax ID7113

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Myotropic; Gut contractile activity

TargetSpodoptera frugiperda isolated gut

Activity0.1-10 nM

Methodisolated gut contraction assay

Half-LifeMammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0247577 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyKinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0403038 VERIFIED: NO

Provenance & Taxonomy

OrganismHelicoverpa zea [Animal]; Heliothis zea [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0432723 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicoverpa zea [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Diuretic; Fluid secretion stimulation

TargetHeliothis virescens isolated Malpighian tubules

MethodMalpighian tubule fluid secretion assay