Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC441H705N125O132S8

DescriptionStandard

        MRTLAILAAILLVALQAQAEPLQARGDEVAAAPEEIPADNPEVVVSLAWDESLAPKDSGSRKNMACACRIPSCLAGERRYGTCFYQGRVWAFCC
    

Molecular Weight10126.59 Da

Isoelectric Point (pI)4.99

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0270

GRAVY Index0.13

Hydrophobic Moment 0.48

Boman Index0.08

Instability Index63.74

Aliphatic Index 90.53

Aromaticity 0.0638

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4084.71

LogP -39.94

H-bond Donors 146.0

H-bond Acceptors 138.0

Rotatable Bonds 325.0

Heavy Atoms 706.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238962 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence