Peptide Database

Peptide NameCathelicidin-2 (Bactenecin-5) (Bac5) (OaBac5)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC889H1409N257O249S5

DescriptionStandard

        METQGASLSLGRWSLWLLLLGLVLPSASAQALSYREAVLRAVGQLNERSSEANLYRLLELDPAPNDEVDPGTRKPVSFTVKETVCPRTTQQPPEECDFKENGLVKQCVGTVTLDPSNDQFDINCNELQSVRFRPPIRRPPIRPPFRPPFRPPVRPPIRPPFRPPFRPPIGPFPGRR
    

Molecular Weight19841.60 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)5.49

Net Charge (pH 7.4) 5.19

Charge Density (pH 7.0) 0.0312

GRAVY Index-0.53

Hydrophobic Moment 0.71

Boman Index-0.10

Instability Index67.36

Aliphatic Index 77.50

Aromaticity 0.0739

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8017.15

LogP -90.36

H-bond Donors 272.0

H-bond Acceptors 260.0

Rotatable Bonds 615.0

Heavy Atoms 1400.0

Ring Count 44.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0026677 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyCathelicidin

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Non-hemolytic

TargetGram-negative bacteria

RECORD: Rec_0224597 VERIFIED: NO