MYP_023430
BIM 23127
Neurological / Signaling
▸
Receptor modulation
▸
Agonist
Neurological / Signaling
▸
Receptor modulation
▸
Antagonist
Neurological / Signaling
▸
Signaling peptide
not Standard
8 amino acids
-
contains X representing unresolved or non-standard residue
ACYWXVCA
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0310559
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GtoPdb peptide ligand
Structure & Mods
disulfide-cyclized peptide [Cyclic]
mixed D/L and noncanonical amino-acid peptide [Mixed]
Amidation
2-7
D-Nal1; D-Trp4; Orn5; Nal8; C-terminal amidation
Bio-Activity Profile
Receptor antagonist
Signaling peptide
human urotensin-II (UT) receptor; HEK293 cells
7.54±0.14
pA2 competitive antagonism (Ca2+ mobilization assay)
RECORD: Rec_0432721
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
disulfide-cyclized peptide [Cyclic]
mixed D/L and noncanonical amino-acid peptide [Mixed]
Amidation
2-7
D-Nal1; D-Trp4; Orn5; Nal8; C-terminal amidation
Bio-Activity Profile
Receptor antagonist; Signaling peptide
rat urotensin-II (UT) receptor; HEK293 cells
7.70±0.05
pA2 competitive antagonism (Ca2+ mobilization assay)