Peptide Database

Peptide NameConotoxin Vc5.3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC44H73N13O20S4

DescriptionStandard

        VNCCGIDESCCS
    

Molecular Weight1232.39 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.30

Net Charge (pH 7.4) -2.57

Charge Density (pH 7.0) -0.1918

GRAVY Index0.52

Hydrophobic Moment 0.14

Boman Index0.11

Instability Index42.91

Aliphatic Index 56.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 541.57

LogP -9.02

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 39.0

Heavy Atoms 81.0

Ring Count 0.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000846 VERIFIED: NO

Provenance & Taxonomy

OrganismConus victoriae [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-10; 4-11

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0029600 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 33.3%, E 0.0%, T 33.3%, C 33.3% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic