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MYP_023392
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Basic Information
RL-37
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
37 amino acids
C187H316N56O47
Standard
Sequence
RLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
Physicochemical Analysis
4100.86 Da
11.20
7.76
7.54
0.2096
-0.45
0.75
-0.13
-7.96
89.46
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1714.30
-15.44
60.0
55.0
147.0
290.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0144193 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Cathelicidin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli (MIC 0.25-0.5 uM, 20% TSB in SPB; 0.25-0.5 uM, 5% TSB in SPB; 4 uM, 20TSB in PIL), Pseudomonas aeruginosa (MIC 0.5 uM, 20% TSB in SPB; ND uM, 5% TSB in SPB; 8 uM, 20TSB in PIL), Staphylococcus aureus (MIC 0.5-1 uM, 20% TSB in SPB; ND, 5% TSB in SPB; 0.5 uM, 20TSB in PIL), Enterococcus faecalis (MIC 1-2, 20% TSB in SPB; 1-2 uM, 20TSB in PIL), Candida albicans (MIC >32 uM, 20% TSB in SPB; 16-32 uM, 5% TSB in SPB; >32 uM, 20TSB in PIL). Update: ref 10/2012; 7/2021
PaperRL-37, an alpha-helical antimicrobial peptide of the rhesus monkey.
RECORD: Rec_0187624 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Cathelicidin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 710A
PMID11557457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557457/
RECORD: Rec_0240404 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Cathelicidin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA ATCC 33591
PMID11557457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557457/
RECORD: Rec_0249108 VERIFIED: NO
Provenance & Taxonomy
Macaca tonkeana [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperAntibacterial protein LL-37 Evidence URLhttps://www.uniprot.org/uniprotkb/Q1KLX6/entry
RECORD: Rec_0249518 VERIFIED: NO
Provenance & Taxonomy
Rhesus monkey [Animal]; Mammalia [Animal]
33208; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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