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MYP_023392
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Basic Information
RL-37
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
37 amino acids
C187H316N56O47
Standard
Sequence
RLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
Physicochemical Analysis
4100.86 Da
11.20
7.76
7.54
0.2096
-0.45
0.75
-0.13
-7.96
89.46
0.0811
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1714.30
-15.44
60.0
55.0
147.0
290.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032880 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Cathelicidin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 49741
PMID11557457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557457/
RECORD: Rec_0036944 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0089900 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Cathelicidin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 930918-3
PMID11557457 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11557457/
RECORD: Rec_0104412 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0112380 VERIFIED: NO
Provenance & Taxonomy
Papio papio [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperAntibacterial protein LL-37 Evidence URLhttps://www.uniprot.org/uniprotkb/Q1KLX3/entry
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