Peptide Database

Peptide NameM5G-pleurain-A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC133H220N36O37S2

DescriptionStandard

        SIITGTKEAKLPQLWKQIACRLYNTC
    

Molecular Weight2979.52 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0938

GRAVY Index-0.15

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index46.47

Aliphatic Index 97.69

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1205.50

LogP -10.44

H-bond Donors 44.0

H-bond Acceptors 42.0

Rotatable Bonds 99.0

Heavy Atoms 208.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027031 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity30 μg/mL

MethodMIC

RECORD: Rec_0034717 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity60 μg/mL

MethodMIC

RECORD: Rec_0038235 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity120 μg/mL

MethodMIC

RECORD: Rec_0367693 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity15 μg/mL

MethodMIC