Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC148H254N46O45S4

DescriptionStandard

        LQKQFCSLRSGRCALLTCLPKEEQIGRCSLSG
    

Molecular Weight3526.14 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.0851

GRAVY Index-0.11

Hydrophobic Moment 0.41

Boman Index-0.10

Instability Index72.90

Aliphatic Index 88.44

Aromaticity 0.0312

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1499.39

LogP -17.94

H-bond Donors 57.0

H-bond Acceptors 52.0

Rotatable Bonds 122.0

Heavy Atoms 243.0

Ring Count 2.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107760 VERIFIED: YES

Provenance & Taxonomy

OrganismAcinonyx jubatus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)