Peptide Database

Peptide NameUnnamed

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory expression optimization

Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC77H132N18O22S2

DescriptionStandard

        MKLSTILFTACATLAAA
    

Molecular Weight1726.11 Da

Isoelectric Point (pI)7.98

Net Charge (pH 7.0)0.49

Net Charge (pH 7.4) 0.26

Charge Density (pH 7.0) 0.0288

GRAVY Index1.49

Hydrophobic Moment 0.25

Boman Index0.47

Instability Index41.59

Aliphatic Index 121.18

Aromaticity 0.0588

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 635.86

LogP -5.37

H-bond Donors 24.0

H-bond Acceptors 25.0

Rotatable Bonds 55.0

Heavy Atoms 119.0

Ring Count 1.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042817 VERIFIED: YES

Provenance & Taxonomy

OrganismYarrowia lipolytica CLIB122 [Fungus]

FamilySignal peptide

Tax ID284591

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization glucoamylase (TlGAMY) secretion

TargetYarrowia lipolytica JMY2101

Activity3.04

MethodGlucoamylase activity assay

PaperCelinska E, Borkowska M, Bialas W, et al. Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags[J]. Applied Microbiology and Biotechnology, 2018, 102(12): 5221-5233. PMID29704042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29704042/

RECORD: Rec_0342643 VERIFIED: YES

Provenance & Taxonomy

OrganismYarrowia lipolytica CLIB122 [Fungus]

FamilySignal peptide

Tax ID284591

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization alpha-amylase (SoAMY) secretion

TargetYarrowia lipolytica JMY2101

Activity4.17

MethodAmylase activity assay

PaperCelinska E, Borkowska M, Bialas W, et al. Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags[J]. Applied Microbiology and Biotechnology, 2018, 102(12): 5221-5233. PMID29704042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29704042/

RECORD: Rec_0381095 VERIFIED: YES

Provenance & Taxonomy

OrganismYarrowia lipolytica CLIB122 [Fungus]

FamilySignal peptide

Tax ID284591

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization glucoamylase (TlGAMY) secretion

TargetYarrowia lipolytica JMY2101

Activity7.55

MethodGlucoamylase activity assay

PaperCelinska E, Borkowska M, Bialas W, et al. Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags[J]. Applied Microbiology and Biotechnology, 2018, 102(12): 5221-5233. PMID29704042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29704042/

RECORD: Rec_0407625 VERIFIED: YES

Provenance & Taxonomy

OrganismYarrowia lipolytica CLIB122 [Fungus]

FamilySignal peptide

Tax ID284591

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization alpha-amylase (SoAMY) secretion

TargetYarrowia lipolytica JMY2101

Activity1.81

MethodAmylase activity assay

PaperCelinska E, Borkowska M, Bialas W, et al. Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags[J]. Applied Microbiology and Biotechnology, 2018, 102(12): 5221-5233. PMID29704042 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29704042/