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MYP_023289
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Basic Information
Tetramer of peptide-paclitaxel conjugate
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KXCKXCKXCKXC
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012079 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Aib = 1-amino-isobutyric acid ,Pac = Paclitaxel
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
0.00064 μM
IC50
PMID17787026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17787026/
RECORD: Rec_0018429 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Aib = 1-amino-isobutyric acid ,Pac = Paclitaxel
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
0.00096 μM
IC50
PMID17787026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17787026/
RECORD: Rec_0132021 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Aib = 1-amino-isobutyric acid ,Pac = Paclitaxel
Bio-Activity Profile
Anticancer
DU
0.0013 μM
IC50
PMID17787026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17787026/
RECORD: Rec_0175039 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Aib = 1-amino-isobutyric acid ,Pac = Paclitaxel
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7
0.00062 μM
IC50
PMID17787026 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17787026/