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MYP_023111
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Basic Information
Ghrelin
Cardiovascular
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
28 amino acids
C141H235N47O41
Standard
Sequence
GSSFLSPEHQRVQQRKESKKPPAKLQPR
Physicochemical Analysis
3244.66 Da
11.07
4.85
4.59
0.1732
-1.68
0.42
-0.49
73.35
41.79
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1460.20
-17.81
49.0
47.0
110.0
229.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259943 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Ghrelin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
RECORD: Rec_0384158 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Ghrelin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
n-octanoyl group at ser 3
Bio-Activity Profile
Growth hormone secretagogue Appetite stimulation
Competitive Radioimmunoassay
Human plasma, in vivo; 1260 s
PMID18697865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18697865/
RECORD: Rec_0392869 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0420227 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Motilin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Gastrointestinal
PMID12414809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12414809/
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