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MYP_023111
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Basic Information
Ghrelin
Cardiovascular
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
28 amino acids
C141H235N47O41
Standard
Sequence
GSSFLSPEHQRVQQRKESKKPPAKLQPR
Physicochemical Analysis
3244.66 Da
11.07
4.85
4.59
0.1732
-1.68
0.42
-0.49
73.35
41.79
0.0357
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1460.20
-17.81
49.0
47.0
110.0
229.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009407 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
n-octanoyl at Ser3
Bio-Activity Profile
Hormonal Appetite regulation
Human plasma after i.v. injection (1 μg/kg)
Competitive radioimmunoassay
21 ± 3 min
PaperEstrogen elevates the peak overnight production rate of acylated ghrelin
RECORD: Rec_0024895 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Ghrelin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP18163
RECORD: Rec_0129500 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Proghrelin-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
n-octanoyl at Ser3
Bio-Activity Profile
Hormonal Appetite regulation
Human plasma after i.v. injection (3 μg/kg)
Competitive radioimmunoassay
45 min
PaperEstrogen elevates the peak overnight production rate of acylated ghrelin
RECORD: Rec_0198704 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0225217 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Ghrelins
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation Feeding regulator
Experimental: 21±3.0 minutes; /1260 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Ghrelins-28 (Homo sapiens): PMID 12414809##18697865 PMID12414809;18697865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12414809/
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