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MYP_023071
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Basic Information
M-lycotoxin-Hc2a (M-LCTX-Hc2a; Lycotoxin-2; Lycotoxin II; spiders, Arthropods, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
27 amino acids
C149H245N39O35S2
Standard
Sequence
KIKWFKTMKSIAKFIAKEQMKKHLGGE
Physicochemical Analysis
3206.91 Da
10.22
5.85
5.58
0.2167
-0.66
0.68
-0.11
6.69
65.19
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1230.70
-6.43
43.0
44.0
118.0
225.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090556 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 10464975 B2 Evidence URLhttps://patents.google.com/patent/US10464975B2/en PatentUS 10464975 B2
RECORD: Rec_0094616 VERIFIED: YES
Provenance & Taxonomy
Hogna carolinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Israelensis
10-60 μM
MIC
PMID9442044;18098329 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9442044/
RECORD: Rec_0123269 VERIFIED: YES
Provenance & Taxonomy
Hogna carolinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida glabrata ATCC 2001
100-150 μM
MIC
PMID9442044;18098329 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9442044/
RECORD: Rec_0131597 VERIFIED: YES
Provenance & Taxonomy
Hogna carolinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli D31
10 μM
MIC
PMID9442044;18098329 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9442044/
RECORD: Rec_0196216 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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