Peptide Database

Peptide NameNigroain-H antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC114H187N23O27S2

DescriptionStandard

        FTMKKSLLLIFFLGTISLSLC
    

Molecular Weight2375.97 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0832

GRAVY Index1.55

Hydrophobic Moment 0.21

Boman Index0.50

Instability Index5.48

Aliphatic Index 148.57

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 798.51

LogP -2.50

H-bond Donors 30.0

H-bond Acceptors 31.0

Rotatable Bonds 80.0

Heavy Atoms 166.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069991 VERIFIED: YES

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0346148 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana nigrovittata [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)