Peptide Database

Peptide NameHuman drosomycin-like defensin

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H187N43O39S2

DescriptionStandard

        QPSGRSGHEVGRPLPHCGPSHHCGSYLD
    

Molecular Weight2968.21 Da

Isoelectric Point (pI)7.08

Net Charge (pH 7.0)0.10

Net Charge (pH 7.4) -0.34

Charge Density (pH 7.0) 0.0034

GRAVY Index-1.01

Hydrophobic Moment 0.75

Boman Index-0.11

Instability Index56.70

Aliphatic Index 38.21

Aromaticity 0.0357

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1271.22

LogP -17.81

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 88.0

Heavy Atoms 208.0

Ring Count 9.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319817 VERIFIED: YES

Provenance & Taxonomy

OrganismGulo gulo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)