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MYP_022972
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Basic Information
cTat
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C56H111N31O12S
Standard
Sequence
CRKKRRQRRR
Physicochemical Analysis
1442.75 Da
12.00
7.75
7.53
0.7748
-3.58
0.51
-1.87
232.70
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
791.75
-10.21
33.0
21.0
55.0
100.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027566 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Conjugated with Insulin
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID19228019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19228019/
RECORD: Rec_0126057 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Cargo conjugation
None
N-term detail: Conjucated to Insulin; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Rat alveolar epithelial cell monolayers (RAECM); HepG2
Cellular uptake assay
PMID19228019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19228019/
RECORD: Rec_0158064 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Insulin
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID19228019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19228019/
RECORD: Rec_0212885 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Insulin
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID19228019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19228019/
RECORD: Rec_0217344 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Insulin
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19228019 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19228019/