Peptide Database

Peptide NameDefensin BmKDfsin4 (4 kDa defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antiviral

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC313H498N90O79S9

DescriptionStandard

        MKTIVLLFVLALVFCTLEMGIVEAGFGCPFNQGQCHKHCQSIRRRGGYCDGFLKQRCVCYRK
    

Molecular Weight7074.44 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)5.61

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0904

GRAVY Index0.23

Hydrophobic Moment 0.58

Boman Index0.07

Instability Index49.05

Aliphatic Index 83.23

Aromaticity 0.1129

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2729.07

LogP -22.58

H-bond Donors 103.0

H-bond Acceptors 96.0

Rotatable Bonds 237.0

Heavy Atoms 491.0

Ring Count 10.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067757 VERIFIED: NO

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyDefensin

Tax ID34649

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0144003 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-MRSA Antiviral Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0179216 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-MRSA Antiviral Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic

TargetHepatitis B

RECORD: Rec_0259153 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-MRSA Antiviral Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0295219 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-MRSA Antiviral Anti-Hepatitis Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic

TargetStaphylococcus aureus (Gram-positive)