Peptide Database

Peptide NameSLAY-screened peptide P3090

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC25H39N5O7

DescriptionStandard

        YLIN
    

Molecular Weight521.61 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0602

GRAVY Index0.88

Hydrophobic Moment 0.51

Boman Index0.48

Instability Index7.50

Aliphatic Index 195.00

Aromaticity 0.2500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 213.94

LogP -0.23

H-bond Donors 7.0

H-bond Acceptors 7.0

Rotatable Bonds 15.0

Heavy Atoms 37.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214566 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/