Peptide Database

Peptide NameConantokin-G

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard Statusnot Standard

Sequence Length17 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        GEXXLQXNQXLIRXKSN
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432697 VERIFIED: YES

Provenance & Taxonomy

OrganismConus geographus [Animal]

Structure & Mods

Bio-Activity Profile

Function

NMDA receptor antagonist Neuroactive Toxin

TargetNR2B-containing N-methyl-D-aspartate (NMDA) receptor; murine cortical neurons

Activity480 nM

MethodIC50 (whole-cell voltage-clamp NMDA-evoked current inhibition)

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