Peptide Database

Peptide NameFIV Egp (746-780)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC194H291N49O55S

DescriptionStandard

        FYEIIMDIEQNNVQGKKGIQQLQKWEDWVGWIGNI
    

Molecular Weight4221.75 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.0638

GRAVY Index-0.54

Hydrophobic Moment 0.67

Boman Index0.08

Instability Index62.28

Aliphatic Index 94.57

Aromaticity 0.1429

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1729.60

LogP -10.96

H-bond Donors 56.0

H-bond Acceptors 54.0

Rotatable Bonds 144.0

Heavy Atoms 299.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369309 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetFeline immunodeficiency virus (FIV):inhibition of cell-cell fusion between FIV/CrFK cells and HeLa cells

Activity2.346 μM

MethodEC50

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