MYP_022894
Abciximab
Hemostasis
▸
Anticoagulant activity
Hemostasis
▸
Antithrombotic activity
Standard
217 amino acids
C1040H1602N264O334S6
Standard
EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQRPEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIE
23339.80 Da
5.92
-1.94
-2.39
-0.0090
-0.21
0.63
0.09
43.02
73.18
0.1014
46870.00
47120.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0293359
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]
Fab fragment
9606;10090
Structure & Mods
linear multidomain protein biologic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Monoclonal antibody
Antiplatelet
Following intravenous bolus administration, free plasma concentrations of Abciximab decrease rapidly with an initial half-life of less than 10 minand a second phase half-life of approx. 0.5 h, probably related to rapid binding to the platelet GPIIb
RECORD: Rec_0391826
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Mus musculus [Animal]
Fab fragment
9606;10090
Structure & Mods
linear multidomain protein biologic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Monoclonal antibody
Anticoagulant
Antithrombotic
Antiplatelet
Following intravenous bolus administration, free plasma concentrations of Abciximab decrease rapidly with an initial half-life of less than 10 minand a second phase half-life of approx. 0.5 h, probably related to rapid binding to the platelet GPIIb