Peptide Database

Peptide NameLysM peptidoglycan-binding domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length2226 amino acids

Chemical FormulaC10754H16692N2982O3523S41

DescriptionStandard

        MITEKLYKEYVEQVKGLEGFRSTVYLDSKGVPTVGYGYALMVYHSGIEPKWVVRNQKALRKVGLNLKDEEYKIIEKYAYAKSSNEPLGSLRSQIESIGIRIDTNTAEGLTRSAIDEAHNTIVSSIGQKTWNGLSHGQQMGVMDRCYQHGNIKPLAKHIISGNTAKVAETMRNDVGYKARAEHRAYLYENDKVPKYVHVVQSGESFGKIARKHSTTQDNLKKLNPGIDVNRLHVWQHVNVRQEIGNSADMIKPGEELRAQRTDAHNVWNRGYDWTWYSPLSWIGKVWNGASSGIVGTYRSSEMRHRIFEDYRPKFTEFSLFPSVVDGLRFHETPLVNEPSWLYRRPGTGEEPEGYIKKVLKELDLKDNILKTFREEAKLCLLSLSCTETVSTLLDTVARKYSYTPWAMYDKVSVIKEAHDIAQDEAESSVWMWSMLKSATFGMWTNTLREELGYAASHVSPLVLDLNGDGVKLVPYTRGVYFDIDNDGFAERVGWLSEQDGHLARDLNKNGRIDDITELFGDDLISAFFKLSLSDSNGDKVIDDRDEDFKELLIWQDKNTNGYSEAKELRSLKDMGIKSISLHTEPDNRIIEGNTITSKSNFTYTDGRQGEVADVHYHNDDMDSWYKGKVSDYKMDEDKYFGEIERFRKEVLEELSSKVEEPGDTDKRSDWVAAVIEEIAVKYINRHKEQHAYGLQEVLQKLETKNVQGRSESLQVCKEGASRLVEEVSEERIQKQYEIVSRVLNATIQNRTNITARYTQEYLKAKDELLNEINDKLAQEKKDINAQKTQEYQEKLKGILAGINVQSKQKAEELYQSVLGGRLAHSVYAQVLASHKAHFVQEYETQKNTWKAFYEGEATREIGKAVKRYSEEYQKQLAIVKERYTKGAREEVDAVNGNYTKWRLTGLEQESEELKNATDSKLSQVLHTHMHSCVKEKEGIRGVLHDQYLKHKDAGSSVLEGYSVLIKQEANKIYQFFTTRIARYLEELYEEESGSYFFGSGRHVSIDTVPEWLEDECFKERESGANNDDMGVKIDPETLFMPLIRGYGKISSLHISMTHNPRLKKLVSDLMVSKLSELNSIYDRVIEILYEWAGVSDIEEDERATAEGINIEARKVAFVERFTGQDFRQLGAAKFVGQHASTAVQKAYDIGLVRITKNLLVQGPFLGIFPNAEYSFIDDSIKLNASLTEIICASKELALRYDLGHDFWIQLSYILSQSLGELDVDLRELKSRLSEAAGEEMFVDSEDVGLVGNESDNIIKGSLGSDYIKGLGGHDKLYGKERSDHLDGGEGSDELFGGQGIDRLYGGGGNDKVYGGDGRDFIYGEGGNDQLYGEDGDDHIEGGSGGDTMDGGAGVNTLSYGTSPIGVHVSLLSGVQEQQEKVEGREDHASGDVFRNFQNLGGSEYNDHLLGDADANHINGEGGDDTIEGLGGNDRLFGATGNDRLLGGEGDDVLSGFDGPDHMDGGEGRDTAHYNHPYSTVGVVVDLSRQRGTGGYAHEDSYISIENVIGSKYRDVIQGDAGNNVLQGMEGDDDIKGADGDDVIYGGRGFDKLLGEEGNDEILLTGDGDHAVGGAGKDSVSYRLASKGVTLNLRQGIGSTHGVHQDKLEEFENVVGSQFDDNIEGDAQANVLYGGKGDDALKGGCGADTISGGEGKDKINGEEGDDIILGDEGEDEIDGGAGIDIVDYSKELASGIKVDLVFGRVSGGIGQNDRLKNIEGVIGTKFNDVLIGGDGNDLLFGGDGDDEIRGGKGNDQLSGGTGKNTIDGGEGNDLCSYASSQEGINVNLSEGKGFKKGIYEDIYTDIEGIIGSRYNDRIIGDDNSNQLFGGDGDDYINGGGWSDKISGGKGNNVLDGGTGRDEFFVAEGSNEVDGGDGNDTANYVEYRREEFTDVHGSEFAIRLRPNLLPQYVGQAFSTPPVSNIPGLVINLVSGKVVKPMGLKDMLSNIENVIGSHFNDTLIGDDTGNDLDGGNGSDTIYGGGGDDRITCGWGMSSLYGGDGNDYFMLKGFTAGIEGGEGRDLADFMNIPISVDVNLKEGYVLYNDIAVIRSRIVGIEGIMGSRLNDTIRDDDGDNIIAGGSGDDKIYVTMGKDSVNGQEGNDTIYVGGNGSKEIWGGSFDADTFVITKDFKAQDRISSVIVDFDAGAGGDKIDLREFGHLKTMEDLRLEEFTHDGKGFIVASLSHESWISLYGVDINKLTNENFIFASDGLKGEYSEYWYEAGASH
    

Molecular Weight245436.10 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-140.39

Net Charge (pH 7.4) -144.28

Charge Density (pH 7.0) -0.0631

GRAVY Index-0.57

Hydrophobic Moment 0.85

Boman Index-0.04

Instability Index28.81

Aliphatic Index 79.38

Aromaticity 0.0849

Extinction Coeff. Reduced 290050.00

Extinction Coeff. Oxidized 290675.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059373 VERIFIED: NO

Provenance & Taxonomy

OrganismRickettsiales endosymbiont of Peranema trichophorum [Bacterium]

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Toxin Non-hemolytic

MethodQualitative functional evidence