Peptide Database

Peptide NameVv-AMP1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC118H195N43O41S4

DescriptionStandard

        RACESQSHRFKGTCVRQSNCAAVCQTE
    

Molecular Weight3000.33 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)1.82

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0673

GRAVY Index-0.71

Hydrophobic Moment 0.45

Boman Index-0.30

Instability Index68.48

Aliphatic Index 32.59

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1408.43

LogP -22.01

H-bond Donors 54.0

H-bond Acceptors 48.0

Rotatable Bonds 101.0

Heavy Atoms 206.0

Ring Count 2.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170117 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli Top10

Activity60 μM

MethodMIC

RECORD: Rec_0394658 VERIFIED: YES

Provenance & Taxonomy

OrganismHelicobacter pylori [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)