Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC337H528N102O102S3

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGRVVSLPEDASAQTQERLRQYNLINDGSTYFDRKKRFMSQ
    

Molecular Weight7736.61 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.86

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.0426

GRAVY Index-0.86

Hydrophobic Moment 0.61

Boman Index-0.18

Instability Index51.09

Aliphatic Index 58.21

Aromaticity 0.1045

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3363.68

LogP -37.15

H-bond Donors 120.0

H-bond Acceptors 109.0

Rotatable Bonds 260.0

Heavy Atoms 544.0

Ring Count 12.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327739 VERIFIED: YES

Provenance & Taxonomy

OrganismOryzias latipes [Animal]

FamilyProgonadoliberin

Tax ID8090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour