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MYP_022815
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Basic Information
Maximin 1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C120H208N32O36
Standard
Sequence
GIGTKILGGVKTALKGALKELASTYAN
Physicochemical Analysis
2675.13 Da
9.83
2.76
2.55
0.1021
0.25
0.55
0.20
7.03
112.22
0.0370
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1105.54
-11.49
39.0
39.0
93.0
188.0
1.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0159624 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Bombina maxima
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
C8166
15.3 μg/mL
IC50
PMID11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835991/
RECORD: Rec_0162182 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer Spermicidal
Escherichia coli ATCC 25922
19.5 μg/mL
MIC
PaperAntimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima.
RECORD: Rec_0174077 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0177500 VERIFIED: NO
Provenance & Taxonomy
Bombina maxima [Animal]; Bombina microdeladigitora [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
RECORD: Rec_0179284 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral Anticancer
Escherichia coli ATCC 25922
19.5 μg/mL
MIC
PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703.; Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima. Peptides. 2002 Mar;23(3):427-435. doi: 10.1016/S0196-9781(01)00641-6. PMID: 11835991. PMID15770703;11835991 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/
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