Peptide Database

Peptide NameCorazonin precursor-related peptide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H212N36O43

DescriptionStandard

        APPAALVTNGHNLGLLDIYDIQDRPTDI
    

Molecular Weight3003.32 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-3.11

Net Charge (pH 7.4) -3.36

Charge Density (pH 7.0) -0.1112

GRAVY Index-0.08

Hydrophobic Moment 0.50

Boman Index0.14

Instability Index44.49

Aliphatic Index 118.57

Aromaticity 0.0357

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1252.39

LogP -11.84

H-bond Donors 40.0

H-bond Acceptors 41.0

Rotatable Bonds 92.0

Heavy Atoms 212.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073626 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila virilis [Animal]

FamilyCorazonin

Tax ID7244

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0176533 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0342023 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila virilis [Animal]

FamilyCorazonin precursor-related peptide

Tax ID7244

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation ACE inhibitory

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour