MYP_022797
Basic Information
Toxin Pi3
Annotation / Sequence feature Nuclear export signal
Anticancer Cytotoxic anticancer activity Cytotoxic
Immunology Innate immune defense Host defense peptide Host defense activity
Membrane / Ion-channel modulation Ion channel inhibition
Membrane / Ion-channel modulation Potassium channel modulation Potassium channel inhibitor
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Venom / Toxin Toxin
Standard
35 amino acids
C169H273N53O50S7
Standard
Sequence
TISCTNEKQCYPHCKKETGYPNAKCMNRKCKCFGR
Physicochemical Analysis
4071.76 Da
9.24
5.42
5.08
0.1550
-1.15
0.66
-0.35
40.16
14.00
0.0857
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1712.08
-21.28
65.0
64.0
137.0
279.0
6.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0002978 VERIFIED: NO
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-25; 10-30; 14-32
Bio-Activity Profile
Toxin
RECORD: Rec_0171023 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 31.4%, E 22.9%, T 22.9%, C 22.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
RECORD: Rec_0317098 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-25; 10-30; 14-32
Bio-Activity Profile
Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense