Peptide Database

Peptide NameSLAY-screened peptide P4804

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC58H86N16O20S2

DescriptionStandard

        SSNNLNNCYCFI
    

Molecular Weight1391.53 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-0.56

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0467

GRAVY Index-0.07

Hydrophobic Moment 0.35

Boman Index0.08

Instability Index22.82

Aliphatic Index 65.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 616.47

LogP -8.64

H-bond Donors 22.0

H-bond Acceptors 22.0

Rotatable Bonds 43.0

Heavy Atoms 96.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083589 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/