Peptide Database

Peptide NameIPB02(SARS-CoV-2-S (1169-1203)-K)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC174H299N49O59

DescriptionStandard

        ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELK
    

Molecular Weight4021.53 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0619

GRAVY Index-0.19

Hydrophobic Moment 0.70

Boman Index-0.02

Instability Index40.22

Aliphatic Index 138.06

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1807.90

LogP -18.59

H-bond Donors 59.0

H-bond Acceptors 57.0

Rotatable Bonds 145.0

Heavy Atoms 282.0

Ring Count 0.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363685 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermChol

Bio-Activity Profile

Function

Antimicrobial Anti-SARS-CoV-2

Targetinhibition of Pseudovirus (PsV) infection in 293T/ACE2 cells

Activity0.08±0.017 μM

MethodIC50

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