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MYP_022752
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Basic Information
Ano-1β (variant of Anoplin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C55H105N15O12
Standard
Sequence
ALLKRIKTLL
Physicochemical Analysis
1168.52 Da
11.17
2.79
2.60
0.2794
0.85
0.57
0.07
24.62
205.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.09
17.0
15.0
42.0
82.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0252666 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0258992 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
8 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0262371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 86
4 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0293751 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PMID15635634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15635634/
RECORD: Rec_0311569 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
32 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
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