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MYP_022752
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Basic Information
Ano-1β (variant of Anoplin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C55H105N15O12
Standard
Sequence
ALLKRIKTLL
Physicochemical Analysis
1168.52 Da
11.17
2.79
2.60
0.2794
0.85
0.57
0.07
24.62
205.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
459.39
-1.09
17.0
15.0
42.0
82.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021802 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0097467 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
8 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0112107 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
128 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0227370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
pneumonia ATCC 700603
32 μg/mL
MIC
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
RECORD: Rec_0246148 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The residue A at position 1 indicates the β-Ala
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic Anticancer
PMID32654770 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32654770/
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