Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC395H646N110O101S7

DescriptionStandard

        MATRSVLLALVVLDLLFYVPPGRSGPNVYIQKLFASCWRLRGSCRQKCLKKEEYHILCDTTRLCCVNPKHLPILTGK
    

Molecular Weight8776.49 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)7.61

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.0989

GRAVY Index0.14

Hydrophobic Moment 0.65

Boman Index0.03

Instability Index62.92

Aliphatic Index 107.53

Aromaticity 0.0779

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3375.73

LogP -25.84

H-bond Donors 125.0

H-bond Acceptors 118.0

Rotatable Bonds 287.0

Heavy Atoms 613.0

Ring Count 14.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115263 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0366132 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic