Peptide Database

Peptide NamePREDICTED: liver-expressed antimicrobial peptide 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC384H641N119O102S8

DescriptionStandard

        MWHLKLCAVLMIFLLLLGQIDGSPIPEVSSAKRRPRRMTPFWRGVSLRPIGASCRDDSECITRLCRKRRCSLSVAQE
    

Molecular Weight8813.45 Da

Isoelectric Point (pI)10.31

Net Charge (pH 7.0)7.55

Net Charge (pH 7.4) 7.20

Charge Density (pH 7.0) 0.0981

GRAVY Index-0.04

Hydrophobic Moment 0.68

Boman Index-0.09

Instability Index75.51

Aliphatic Index 96.23

Aromaticity 0.0519

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3562.47

LogP -32.97

H-bond Donors 135.0

H-bond Acceptors 119.0

Rotatable Bonds 293.0

Heavy Atoms 613.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020388 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

Tax ID9598

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0023450 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyLEAP-2

Tax ID9595

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0041477 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLEAP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetBacillus megaterium

Paper人Ⅱ型肝脏表达抗菌肽LEAP-2的生物信息学分析; Bioinformatics Analysis of Human Liver-expressed Antimicrobial Peptide 2. [J].基因组学与应用生物学,2022,41(02):407-414. DOI:10.13417/j.gab.041.000407. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37200

RECORD: Rec_0084971 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyLEAP2

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic