Peptide Database

Peptide NameTrp-8 gonadoliberin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Cell-cell communication

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC60H75N15O14

DescriptionStandard

        QHWSYGLWPG
    

Molecular Weight1230.33 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0154

GRAVY Index-0.92

Hydrophobic Moment 0.23

Boman Index0.26

Instability Index21.31

Aliphatic Index 39.00

Aromaticity 0.3000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 460.24

LogP -1.80

H-bond Donors 16.0

H-bond Acceptors 15.0

Rotatable Bonds 32.0

Heavy Atoms 89.0

Ring Count 7.0

Amide Bonds 10.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0119502 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyTrp-8 gonadoliberin

Tax ID71582

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0266543 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication Hormones