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MYP_022710
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Basic Information
Lys-15, Lys-16
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H162N22O19
Standard
Sequence
GLLGPLLKIAAKVGKKLL
Physicochemical Analysis
1832.36 Da
10.48
3.76
3.55
0.2087
0.93
0.68
0.31
-18.86
178.89
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
653.31
-1.43
22.0
23.0
65.0
129.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacteria: Escherichia coli ATCC 25726
50 μM
MIC
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0258098 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 900280
6 μM
MIC
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0267346 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
Hemolysis against human erythrocytes
60 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0295766 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Cancer:hepatoma‐derived cells HepG2
10 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0312385 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 55.6%, E 0.0%, T 11.1%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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