MYP_022696
Basic Information
L-13
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
not Standard
23 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXRPRPYSPRPTSHPRPIRVCXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0106456 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,22; non-canonical residue code at 23; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity, x = SMCC = succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
64 μg/mL
MIC
RECORD: Rec_0184185 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,22; non-canonical residue code at 23; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity, x = SMCC = succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli sbmA
64 μg/mL
MIC
RECORD: Rec_0185342 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,22; non-canonical residue code at 23; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity, x = SMCC = succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 19606
64 μg/mL
MIC
RECORD: Rec_0301761 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,22; non-canonical residue code at 23; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity, x = SMCC = succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
64 μg/mL
MIC
RECORD: Rec_0324918 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,22; non-canonical residue code at 23; peptide is the all-L and all-D form, respectively, lower case letters denote D form. suffix m = conjugate containing a control PNA with two mismatched (interchanged) nucleobases, X = 6-aminohexanoic acid = H2N-(CH2)5COOH residue, Anti-acpP: B= PNA2301 = H-CTCATACTCT-NH2, Mismatch: J = PNA3961 = H-CTCTTACACT-NH2, O = Mal= polar maleimide linker, Z = eg1= Ethylene glycol moeity, x = SMCC = succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 13883
4-8 μg/mL
MIC
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