Peptide Database

Peptide NameHR2L

Function Ontology

Antiviral

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC229H366N54O74S

DescriptionStandard

        SIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNY
    

Molecular Weight5091.74 Da

Isoelectric Point (pI)4.18

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0785

GRAVY Index0.01

Hydrophobic Moment 0.61

Boman Index0.15

Instability Index10.28

Aliphatic Index 119.11

Aromaticity 0.0889

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2097.63

LogP -19.18

H-bond Donors 70.0

H-bond Acceptors 72.0

Rotatable Bonds 171.0

Heavy Atoms 358.0

Ring Count 5.0

Amide Bonds 51.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0349034 VERIFIED: YES

Provenance & Taxonomy

OrganismMiddle East respiratory syndrome-related coronavirus isolate United Kingdom,H123990006,2012 [Virus]

FamilyHR2-derived fusion inhibitor

Tax ID1263720

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetMiddle East respiratory syndrome-related coronavirus isolate United Kingdom/H123990006/2012

Activity0.5 μM

MethodIC50