Peptide Database

Peptide NameHepcidin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC416H644N112O134S13

DescriptionStandard

        MKTFSVAVAVTLVLAFICLQESSAGSFTEVQELEEPMNNESPVAAHEEKSEESWKMPYNNRHKRSPKDCQFCCGCCPDMSGCGPCCKY
    

Molecular Weight9775.08 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-4.39

Net Charge (pH 7.4) -4.87

Charge Density (pH 7.0) -0.0499

GRAVY Index-0.37

Hydrophobic Moment 0.47

Boman Index-0.02

Instability Index83.41

Aliphatic Index 48.75

Aromaticity 0.0795

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3927.80

LogP -44.40

H-bond Donors 140.0

H-bond Acceptors 145.0

Rotatable Bonds 319.0

Heavy Atoms 675.0

Ring Count 16.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426979 VERIFIED: NO

Provenance & Taxonomy

OrganismEpinephelus moara [Animal]

FamilyHepcidin

Tax ID300413

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal