Peptide Database

Peptide NamePro-Bac8c

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC88H135N27O25

DescriptionStandard

        EEEEAAAGRLWVLWRR
    

Molecular Weight1971.18 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.33

Charge Density (pH 7.0) -0.0722

GRAVY Index-0.78

Hydrophobic Moment 0.55

Boman Index-0.21

Instability Index130.59

Aliphatic Index 85.62

Aromaticity 0.1250

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 866.30

LogP -5.19

H-bond Donors 32.0

H-bond Acceptors 24.0

Rotatable Bonds 64.0

Heavy Atoms 140.0

Ring Count 4.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0432672 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermAmidation

Other ModsN-terminal acetylation; C-terminal amidation; D-amino-acid Bac8c segment

Bio-Activity Profile

Function

Cytotoxic

TargetCFBE41o− human bronchial epithelial cells

Activity>300 μM

MethodIC50

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