Peptide Database

Peptide NameRelaxin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC109H182N36O35S5

DescriptionStandard

        ESGGLMSQQCCHVGCSRRSIAKLYC
    

Molecular Weight2717.16 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)1.88

Net Charge (pH 7.4) 1.60

Charge Density (pH 7.0) 0.0753

GRAVY Index-0.09

Hydrophobic Moment 0.47

Boman Index-0.06

Instability Index106.65

Aliphatic Index 62.40

Aromaticity 0.0400

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1164.85

LogP -15.85

H-bond Donors 46.0

H-bond Acceptors 43.0

Rotatable Bonds 92.0

Heavy Atoms 185.0

Ring Count 2.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012310 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyRelaxin

Tax ID10090

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-15

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0221923 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0229864 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0415830 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyInsulin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic