Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2257H3639N581O643S17

DescriptionStandard

        MIFSVFPTAKMFPCCWLALVALIPVTLSTNPGVKVKLTAKGLEYGRQLGMASIQKKLKTIKVPDMSGTQKVPTIGKVRYSLTNLKIVDVGLPKSTLDLVPGTGVRLSIDNAFISLHGNWRVKYLRIIKDSGSFDLKVSGLTITTSIAIKSDETGRPVVSSVNCVTAVGSVSIKFHGGASWLYNLFKKFIDKALRKALEKQICNLVADVVSDLNLQLKTLNVVAKVDQYADIEYSMVSAPTVSKASIELGMKGEFYNTGKHREPPFSPAAFSLPPETNNMLYIGLSAFTANSAAFVYNTAGALSLYITDDMIPQGSPIRLNTRTFGTFIPQIAKRFPGLMMKLLVRTAKNPVVTFEPNNATVDATCTVTAYAIHPNATLSPLFVLNLETSVSARVFVSGTRLAGAVSLNKMALTLETSYVGDAQSLPGYPLPTLGKMKLVNTQLQVLKDYVLIGTDVQFTG
    

Molecular Weight49746.65 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)18.80

Net Charge (pH 7.4) 18.21

Charge Density (pH 7.0) 0.0409

GRAVY Index0.21

Hydrophobic Moment 0.84

Boman Index0.15

Instability Index24.35

Aliphatic Index 101.70

Aromaticity 0.0804

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151216 VERIFIED: NO

Provenance & Taxonomy

OrganismCyclopterus lumpus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria