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MYP_022502
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Basic Information
Pb-CATH1 Python bivittatus antimicrobial peptides peptide derivative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
31 amino acids
C187H312N54O34
Standard
Sequence
KRVKRFKKFFRKIKKGFRKIFKKTKIFIGGT
Physicochemical Analysis
3860.82 Da
12.00
14.75
14.53
0.4758
-0.79
1.04
-0.37
7.63
59.68
0.1935
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1510.60
-7.63
57.0
49.0
144.0
275.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019162 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC 29213)
128 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0049957 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cell
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0078315 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0127253 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli (ATCC 25922)
2 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
RECORD: Rec_0173471 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus (ATCC 10876)
46 μg/mL
MIC
PaperGenomewide Analysis of the Antimicrobial Peptides in Python bivittatus and Characterization of Cathelicidins with Potent Antimicrobial Activity and Low Cytotoxicity. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00530-17. doi: 10.1128/AAC.00530-17. PMID: 28630199. PMID28630199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28630199/
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