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MYP_022484
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Basic Information
Pleurocidin [G1A][G3A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C131H196N36O29
Standard
Sequence
AWASFFKKAAHVGKHVGKAALTHYL
Physicochemical Analysis
2739.18 Da
10.18
4.05
3.71
0.1621
0.11
0.59
0.20
-1.83
78.40
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.32
-6.24
37.0
36.0
87.0
196.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084149 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
16 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0113044 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa IFO 12582
64 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0114028 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
100 μM
Hemolysis
PaperYoshida K, Mukai Y, Niidome T, et al. Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. J Pept Res. 2001 Feb;57(2):119-126. doi:10.1034/j.1399-3011.2001.00802.x. PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0133236 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Rabbit erythrocytes
100 μM
Hemolysis
PaperYoshida K, Mukai Y, Niidome T, et al. Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. J Pept Res. 2001 Feb;57(2):119-126. doi:10.1034/j.1399-3011.2001.00802.x. PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0151876 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus IFO 12732
8 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
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