Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length195 amino acids

Chemical FormulaC959H1525N263O263S11

DescriptionStandard

        PKTPPMAHEPMLLVAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLSTKSMEVFSPQLQESYPNQPMELHLWARQQPLISCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGGLSPACSMDPPLCAVLGSNLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRPVP
    

Molecular Weight21299.69 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)7.27

Net Charge (pH 7.4) 6.91

Charge Density (pH 7.0) 0.0373

GRAVY Index0.04

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index61.13

Aliphatic Index 89.54

Aromaticity 0.0718

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8232.98

LogP -104.09

H-bond Donors 283.0

H-bond Acceptors 285.0

Rotatable Bonds 667.0

Heavy Atoms 1496.0

Ring Count 43.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116171 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecile atricapillus (Black-capped chickadee) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria