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MYP_022468
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Basic Information
A54145 C
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XWEXTXADKXGNXV
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118034 VERIFIED: YES
Provenance & Taxonomy
Streptomyces fradiae [Bacterium]
A54145
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
8-methyldecanoyl fatty-acyl moiety
Non-proteinogenic/modified monomers: OH-Asn; NMe-Gly; OMe-Asp; 3Me-Glu
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Staphylococcus aureus XI.1
2.0 μg/mL
MIC (agar dilution)
PaperA54145, a new lipopeptide antibiotic complex: microbiological evaluation. J Antibiot. 1990;43:616-622. DOI:10.7164/antibiotics.43.616 PMID2380110
RECORD: Rec_0432659 VERIFIED: YES
Provenance & Taxonomy
Streptomyces fradiae [Bacterium]
A54145
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
8-methyldecanoyl fatty-acyl moiety
Non-proteinogenic/modified monomers: OH-Asn; NMe-Gly; OMe-Asp; 3Me-Glu
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Staphylococcus aureus V41
4.0 μg/mL
MIC (agar dilution)
PaperA54145, a new lipopeptide antibiotic complex: microbiological evaluation. J Antibiot. 1990;43:616-622. DOI:10.7164/antibiotics.43.616 PMID2380110
RECORD: Rec_0432660 VERIFIED: YES
Provenance & Taxonomy
Streptomyces fradiae [Bacterium]
A54145
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
8-methyldecanoyl fatty-acyl moiety
Non-proteinogenic/modified monomers: OH-Asn; NMe-Gly; OMe-Asp; 3Me-Glu
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Staphylococcus aureus X400
4.0 μg/mL
MIC (agar dilution)
PaperA54145, a new lipopeptide antibiotic complex: microbiological evaluation. J Antibiot. 1990;43:616-622. DOI:10.7164/antibiotics.43.616 PMID2380110
RECORD: Rec_0432661 VERIFIED: YES
Provenance & Taxonomy
Streptomyces fradiae [Bacterium]
A54145
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
8-methyldecanoyl fatty-acyl moiety
Non-proteinogenic/modified monomers: OH-Asn; NMe-Gly; OMe-Asp; 3Me-Glu
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Staphylococcus aureus S13E
4.0 μg/mL
MIC (agar dilution)
PaperA54145, a new lipopeptide antibiotic complex: microbiological evaluation. J Antibiot. 1990;43:616-622. DOI:10.7164/antibiotics.43.616 PMID2380110
RECORD: Rec_0432662 VERIFIED: YES
Provenance & Taxonomy
Streptomyces fradiae [Bacterium]
A54145
Structure & Mods
side-chain cyclized peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
8-methyldecanoyl fatty-acyl moiety
Non-proteinogenic/modified monomers: OH-Asn; NMe-Gly; OMe-Asp; 3Me-Glu
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antibiotic
Staphylococcus epidermidis EPi.1
2.0 μg/mL
MIC (agar dilution)
PaperA54145, a new lipopeptide antibiotic complex: microbiological evaluation. J Antibiot. 1990;43:616-622. DOI:10.7164/antibiotics.43.616 PMID2380110
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