Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length265 amino acids

Chemical FormulaC1367H2136N342O388S7

DescriptionStandard

        MEKAILKNLNKMLCPIITSEVEALNANLSMLEVLRSIDNYTLLDYSLISSPEITENYIDLNLKGVFYPLENLTDPPFSSVPFVLPEHSDSMIYIGISEYFFKSASYAYFTAGAFNVTLTTEKIFNHLIRNSQGLGNMLSWVASTNVALAILGQRLICSLSLDRFRLSLPESLRSHIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEGFLLISTDLKYKTSLKQQPSFHGWEALNLISGQWRGKPAPW
    

Molecular Weight29794.10 Da

Isoelectric Point (pI)5.87

Net Charge (pH 7.0)-3.96

Net Charge (pH 7.4) -4.58

Charge Density (pH 7.0) -0.0150

GRAVY Index0.13

Hydrophobic Moment 0.70

Boman Index0.16

Instability Index48.79

Aliphatic Index 111.13

Aromaticity 0.1019

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078962 VERIFIED: NO

Provenance & Taxonomy

OrganismPhocoena sinus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence