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MYP_022448
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Basic Information
PSPHa1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
19 amino acids
C95H151N23O24
Standard
Sequence
FLSLIPKAISAVSALANHF
Physicochemical Analysis
1999.35 Da
8.76
0.85
0.59
0.0445
1.20
0.50
0.46
2.50
138.95
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
736.81
-4.97
25.0
26.0
62.0
142.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0420373 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 43816
256 μM
MIC
PMID30774309 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30774309/
RECORD: Rec_0432652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
8 μM
MBC
PaperStructure-activity relationship of phylloseptin-PHa analogues. DOI:10.2147/DDDT.S191072 PMID30774309
RECORD: Rec_0432653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli NCTC 10418
128 μM
MBC
PaperStructure-activity relationship of phylloseptin-PHa analogues. DOI:10.2147/DDDT.S191072 PMID30774309
RECORD: Rec_0432654 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCYC 1467
32 μM
MBC
PaperStructure-activity relationship of phylloseptin-PHa analogues. DOI:10.2147/DDDT.S191072 PMID30774309
RECORD: Rec_0432655 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus NCTC 12493
32 μM
MBC
PaperStructure-activity relationship of phylloseptin-PHa analogues. DOI:10.2147/DDDT.S191072 PMID30774309
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