Peptide Database

Peptide NameBeta-defensin 125

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC724H1148N192O221S13

DescriptionStandard

        MNLLMLTFIICGLLTQVTKGSFEPPKCWKNNIGHCRRRCLDTERYILVCRNKLSCCISIIISHEYTRRPAFPVIHPEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSKTTTSKTTMPPPSQTALTHN
    

Molecular Weight16494.86 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.28

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index64.00

Aliphatic Index 70.07

Aromaticity 0.0753

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6573.02

LogP -70.62

H-bond Donors 234.0

H-bond Acceptors 238.0

Rotatable Bonds 527.0

Heavy Atoms 1150.0

Ring Count 29.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0317866 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence