Peptide Database

Peptide NameMotilin(1–12)ghrelin(12–18)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC106H165N29O30

DescriptionStandard

        FVPIFTYGELQRVQQRKES
    

Molecular Weight2325.62 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0402

GRAVY Index-0.68

Hydrophobic Moment 0.48

Boman Index-0.16

Instability Index48.61

Aliphatic Index 71.58

Aromaticity 0.1579

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 992.71

LogP -8.35

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 77.0

Heavy Atoms 165.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186093 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.01 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 186 s